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CD74 Polyclonal Antibody

CAT: 0965-JOT-AP01540-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP01540-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD74 molecule encoded by CD74 associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
CAS Number
9007-83-4
Synonyms
CD74; DHLAG; HLA class II histocompatibility antigen gamma chain; HLA-DR antigens-associated invariant chain; Ia antigen-associated invariant chain; Ii; p33; CD74
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human CD74. AA range:161-210
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
33516
Antibody Type
Primary antibody
Isotype
IgG

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