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CD305 Polyclonal Antibody

CAT: 0965-JOT-AP01462-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP01462-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The leukocyte associated immunoglobulin like receptor 1 encoded by LAIR1 is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13. called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
LAIR1; CD305; Leukocyte-associated immunoglobulin-like receptor 1; LAIR-1; hLAIR1; CD305
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human LAIR1. AA range:21-70
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
31412
Antibody Type
Primary antibody
Isotype
IgG

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