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Caspase-6 Polyclonal Antibody

CAT: 0965-JOT-AP01205-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP01205-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CASP6 encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein (caspase 6) is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of CASP6 results in multiple transcript variants that encode different isoforms.
CAS Number
9007-83-4
Synonyms
CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Caspase 6. AA range:223-272
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
33310
Antibody Type
Primary antibody
Isotype
IgG

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