Products for Research Use Only
RegisterLogin

Caspase-3 Polyclonal Antibody

CAT: 0965-JOT-AP01203-01Size: 20 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0965-JOT-AP01203-01Size:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
CASP3 encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein (caspase 3) cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
CAS Number
9007-83-4
Synonyms
CASP3; CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Caspase 3. AA range:116-165
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
31608
Antibody Type
Primary antibody
Isotype
IgG

Related Products

CatalogName
JOT-AP00226-01Caspase 3 p17 Polyclonal Antibody
JOT-PHS00727-01Phospho-Caspase-3 (S150) Polyclonal Antibody
JOT-AP01888-01Cleaved-Caspase-3 p12 (D175) Polyclonal Antibody
JOT-AP01890-01Cleaved-Caspase-3 p17 (D175) Polyclonal Antibody
JOT-AP01889-01Cleaved-Caspase-3 p17 (D175) Polyclonal Antibody
JOT-AP01213-01Caspase-9 Polyclonal Antibody
JOT-AP01192-01Caspase-1 Polyclonal Antibody
JOT-AP07124-01Caspase-8 Polyclonal Antibody
JOT-AP01195-01Caspase-10 Polyclonal Antibody
JOT-AP01207-01Caspase-7 Polyclonal Antibody

Alternative Products

CatalogName
MBS8526185-01Caspase-3 Polyclonal Antibody
BS79641Caspase-3 polyclonal antibody
A71049-050Caspase 3 Polyclonal Antibody

Popular Products