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Caldesmon Polyclonal Antibody

CAT: 0965-JOT-AP01119-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP01119-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CALD1 (caldesmon 1) encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
CAS Number
9007-83-4
Synonyms
CALD1; CAD; CDM; Caldesmon; CDM
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Caldesmon. AA range:744-793
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
high molecular weight (predominantly in smooth muscles) (120-150 KD) and a low molecular weight (60
Antibody Type
Primary antibody
Isotype
IgG

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