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C8 Beta Polyclonal Antibody

CAT: 0965-JOT-AP01053-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP01053-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
C8B (complement C8 beta chain) encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
Complement component C8 beta chain (Complement component 8 subunit beta)
Host
Rabbit
Reactivity
Human;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human C8B. AA range:371-420
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
67047
Antibody Type
Primary antibody
Isotype
IgG