Products for Research Use Only
RegisterLogin

BARD1 Polyclonal Antibody

CAT: 0965-JOT-AP00836-01Size: 20 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0965-JOT-AP00836-01Size:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
BARD1 encodes a protein which interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. This protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. This protein may be the target of oncogenic mutations in breast or ovarian cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for BARD1.
CAS Number
9007-83-4
Synonyms
BARD1; BRCA1-associated RING domain protein 1; BARD-1
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human BARD1. AA range:1-50
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
86648
Antibody Type
Primary antibody
Isotype
IgG

Related Products

CatalogName
JOT-AP00838-01BART1 Polyclonal Antibody
JOT-AP00731-01BARX1 Rabbit Polyclonal Antibody
JOT-AP15592-01YTHD2 Polyclonal Antibody
JOT-AP15626-01ZEB1 Polyclonal Antibody
JOT-AP15515-01VWA3A Polyclonal Antibody
JOT-AP15563-01WWTR1 Polyclonal Antibody
JOT-AP15568-01XDH Polyclonal Antibody
JOT-AP15664-01ZN713 Polyclonal Antibody
JOT-AP15660-01ZN574 Polyclonal Antibody
JOT-AP15554-01WNT7B Polyclonal Antibody

Alternative Products

CatalogName
MBS2536386-01BARD1 Polyclonal Antibody
APRab07466-01BARD1 Rabbit Polyclonal Antibody
TMAB-03025-01Anti-BARD1 Polyclonal Antibody
NBP3-13065Rabbit Polyclonal BARD1 Antibody
BS2408-01BARD1 (R8) polyclonal antibody

Popular Products