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Arrestin-Beta-1 Polyclonal Antibody

CAT: 0965-JOT-AP00632-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP00632-01Size:20 µL
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Background
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.
CAS Number
9007-83-4
Synonyms
ARRB1; ARR1; Beta-arrestin-1; Arrestin beta-1
Host
Rabbit
Reactivity
Human;Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human Arrestin 1. AA range:369-418
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
47066
Antibody Type
Primary antibody
Isotype
IgG

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