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ALK-1 Polyclonal Antibody

CAT: 0965-JOT-AP00373-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP00373-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ACVRL1 (activin A receptor like type 1) encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
CAS Number
9007-83-4
Synonyms
ACVRL1; ACVRLK1; ALK1; Serine/threonine-protein kinase receptor R3; SKR3; Activin receptor-like kinase 1; ALK-1; TGF-B superfamily receptor type I; TSR-I
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human ACVL1. AA range:196-245
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
56124
Antibody Type
Primary antibody
Isotype
IgG