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4E-BP1 Polyclonal Antibody

CAT: 0965-JOT-AP00034-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP00034-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
EIF4EBP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
CAS Number
9007-83-4
Synonyms
EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human EIF4EBP1. AA range:36-85
Clonality
Polyclonal
Applications
IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
12449
Antibody Type
Primary antibody
Isotype
IgG

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