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Anti-Huntingtin

CAT: 0013-GTR18086485Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18086485Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse monoclonal antibody to Huntingtin
Reactivity
Human
Immunogen
N-terminal pepetides 1-225 aa.
Clonality
Monoclonal
Clone
BJXH7
Conjugation
Unconjugated
Concentration
100ug/100ul
Dilution
Western blot and IHC in lipid metabolic research. Huntingtin is a 350kDa protein that is mutated in Huntington's disease (HD) . The normal function of Huntingtin still remains uncertain but it has been suggested that it performs a necessary housekeeping function. The abnormal form of Huntingtin aggregates in vitro and forms neuronal intranuclear and cytoplasmic inclusions in HD patients. This antibody detects a 350KD band on western blots but also detects smaller degradation products_recover of Huntingtin in some tissue lysates.
Form
Liquid
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Western blot and IHC in lipid metabolic research. Huntingtin is a 350kDa protein that is mutated in Huntington's disease (HD) . The normal function of Huntingtin still remains uncertain but it has been suggested that it performs a necessary housekeeping function. The abnormal form of Huntingtin aggregates in vitro and forms neuronal intranuclear and cytoplasmic inclusions in HD patients. This antibody detects a 350KD band on western blots but also detects smaller degradation products_recover of Huntingtin in some tissue lysates.
Tested Applications
IHC, WB
Host or Source
Mouse
Preservative
PBS, pH 7.4 with 0.05% sodium azide.
Isotype
IgG

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