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Anti-LPL

CAT: 0013-GTR18086480Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18086480Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse monoclonal antibody to LPL
Reactivity
Human
Immunogen
Human LPL whole protein
Clonality
Monoclonal
Clone
BNRNXC6
Conjugation
Unconjugated
Field of Research
Metabolism Research
Concentration
100ug/100ul
Dilution
Western blot (1:100) and ELISA (1:200~500) in lipid metabolic research. Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion. Recently, it has also been shown that LPL promotes the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF) secretion, and induction of vascular smooth muscle cell proliferation.
Form
Liquid
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Western blot (1:100) and ELISA (1:200~500) in lipid metabolic research. Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion. Recently, it has also been shown that LPL promotes the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF) secretion, and induction of vascular smooth muscle cell proliferation.
Tested Applications
ELISA, WB
Host or Source
Mouse
Preservative
PBS, pH 7.4 with 0.05% sodium azide.
Isotype
IgG

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