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Ionizable lipid-1

CAT: 0804-HY-156630-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-156630-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure[1].
CAS Number
2055939-68-7
UNSPSC
12352211
Target
Liposome
Type
Oligonucleotides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ionizable-lipid-1.html
Purity
98.0
Solubility
Methanol : 50 mg/mL (ultrasonic)
Smiles
O=C(CCCCCCCCC(CCCCCCCCC(OC(CCCCCC)CCCCCC)=O)N(CCCN(C)C)C(CCCCCCC)=O)OC(CCCCCC)CCCCCC
Molecular Formula
C58H114N2O5
Molecular Weight
919.54
References & Citations
[1]Thomas D Madden, et al. Lamellar lipid nanoparticles. Patent WO2019089828A1.|[2]Ramaswamy S, et al., Systemic delivery of factor IX messenger RNA for protein replacement therapy. Proc Natl Acad Sci U S A. 2017 Mar 7;114 (10) :E1941-E1950.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

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