CD218b Recombinant Protein

CAT: 0384-NCP0341-01Size: 500 µgDry Ice: NoHazardous: No
CAT#:0384-NCP0341-01Size:500 µg
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Background
Interleukin-18 (IL-18) has been identified as a molecule that induces IFN-γ production and enhances NK cell cytotoxicity. IL-18 receptor (IL-18R) is a type I membrane protein present in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta and heart, and absent from brain, skeletal muscle, pancreas and kidney. IL-18R is present in Hodgkin’s disease cell lines, and does not bind IL-1α or IL-1β. The association of IL-18 to IL-18R leads to activation of NFκB. At present two subunits of IL-18R have been characterized: IL-18Rα and IL-18Rβ. IL-18Rα has been described as the ligand-binding chain and IL-18Rβ as the signal-transduction chain.
CAS Number
9000-83-3
Swiss Prot
O95256
Modification Site
NdeI-XhoI
Expression System
Pet-22b (+)
Tag
His-tag
Purity
Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE) .
Solubility
PBS, 4M Urea, PH7.4
Molecular Weight
~43kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Host or Source
E.coli
AA Sequence
MFNISGCSTKKLLWTYSTRSEEEFVLFCDLPEPQKSHFCHRNRLSPKQVPEHLPFMGSNDLSDVQWYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCVKMILEVKPQTNASCEYSASHKQDLLLGSTGSISCPSLSCQSDAQSPAVTWYKNGKLLSVERSNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFERVFNPVIKWYIKDSDLEWEVSVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKR

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Alternative Products

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E43CP0341CD218b Recombinant Protein
PPT-11314Human CD218b/IL18RAP Recombinant Protein
E55P6403Recombinant Human CD218b/IL18RAP Protein, C-Strep
KMH381Recombinant Human CD218B/IL18RAP Protein, His Tag
YHB59001Recombinant Human CD218b/IL18RAP Protein, N-His
EHB59002Recombinant Human CD218b/IL18RAP Protein, C-His
AHB59001Recombinant Human CD218b/IL18RAP Protein, C-His (Active)
EHB59003Recombinant Human CD218b/IL18RAP Protein, C-Fc-His
RP01100-01Recombinant Human IL-18 R beta/IL-1 R7/CD218b Protein
396885IL18RAP, Recombinant, Human, aa20-356, hIgG-His-Tag (Interleukin-18 Receptor Accessory Protein, IL18RAP, ACPL, CD218b, CDw218b, IL-18R-Beta, IL-18RAcP, IL-18Rbeta, IL-1R-7, IL-1R7, IL-1RAcPL, IL18RB) discontinued

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