Products for Research Use Only
RegisterLogin

ROCK1 Recombinant Rabbit mAb

CAT: 0384-BS49605-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS49605-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18. [provided by RefSeq, Aug 2015]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
ROCK-I; P160ROCK
Swiss Prot
Q13464
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human ROCK1
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, FC, IP
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
158 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of ROCK1 in K562, C6 cell lysates using ROCK1 antibody (1:1000 diluted) .
Host or Source
Rabbit

Related Products

CatalogName
BS45233-01ROCK2 Recombinant Rabbit mAb
BZ16583-01ROCK1 polyclonal antibody
MB11540ROCK1 monoclonal antibody
BS91175ROCK1 polyclonal antibody
MB11541ROCK1 monoclonal antibody
PPL01657-1PCR-BluntII-TOPO-ROCK1
BS49223-01Cre recombinase Recombinant Rabbit mAb
BS45310-01Nrf2 Rabbit Recombinant Rabbit mAb
BS45807-01FOXL2 Recombinant Rabbit mAb
BS47946SOX11 Recombinant Rabbit mAb

Alternative Products

CatalogName
ARM1664-01ROCK1 Recombinant Rabbit mAb
CMA5285-01Recombinant Anti-ROCK1 Rabbit mAb
HA750181ROCK1 Recombinant Rabbit monoclonal Antibody
A120323Anti-ROCK1 (Recombinant Rabbit, Monoclonal, IgG)
ET1609-53ROCK1 Recombinant Rabbit Monoclonal Antibody [ST05-19]
S0B1040-01ROCK1 Recombinant Rabbit mAb (S-1304-153)
S0B0868-01ROCK1+ROCK2 Recombinant Rabbit mAb (S-1305-26)
MBS1164269Recombinant Rabbit Rho-associated protein kinase 1 (ROCK1), partial
P1435-01Recombinant Human ROCK1
OPCD06734-50UGROCK1 Recombinant Protein

Popular Products