ENPP1 Recombinant Rabbit mAb

• Background:

  This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance. [provided by RefSeq, Jul 2008]

• Structure Composition:

  Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Product Name Alternative:

  M6S1; NPP1; NPPS; PC-1; PCA1; ARHR2; COLED; PDNP1

• Swiss Prot:

  P22413

• Reactivity:

  Human

• Immunogen:

  A synthetic peptide of human ENPP1

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ICC/IF, FC, IP

• Purity:

  Affinity Purification

• Modification:

  Unmodification

• Molecular Weight:

  140 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of extracts from HepG2 cells at 1:1000.

• Host or Source:

  Rabbit

• CAS Number:

  9000-83-3