SUN2 Recombinant Rabbit mAb

CAT: 0384-BS47890-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS47890-01Size:50 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM) . The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]) .[supplied by OMIM, Nov 2010]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
UNC84B
Swiss Prot
Q9UH99
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human SUN2
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, FC
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
80 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of extracts from HCT116, RAW264.7 cells and Rat muscle tissue using it at 1:2000.
Host or Source
Rabbit

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