Products for Research Use Only

Bag3 Recombinant Rabbit mAb

CAT: 0384-BS47815-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS47815-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
BIS; MFM6; BAG-3; CAIR-1
Swiss Prot
O95817
Reactivity
Human
Immunogen
A synthetic peptide of human Bag3
Conjugation
Unconjugated
Applications
WB, IHC, IP
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
74-80 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of extracts from HeLa cells at 1:1000.
Host or Source
Rabbit