Proteasome 20S alpha 5/PSMA5 Recombinant Rabbit mAb

• Background:

  The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]

• Structure Composition:

  Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Product Name Alternative:

  PSC5; ZETA

• Swiss Prot:

  P28066

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human Proteasome 20S alpha 5/PSMA5

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ICC/IF, FC

• Purity:

  Affinity Purification

• Modification:

  Unmodification

• Molecular Weight:

  26 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of extracts from HepG2 cells using db12987 at 1:1000.

• Host or Source:

  Rabbit

• CAS Number:

  9000-83-3