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SFT Recombinant Rabbit mAb

CAT: 0384-BS47260-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS47260-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
SFT; UBCH5; UBC4/5; UBCH5A; E2 (17) KB1
Swiss Prot
P51668
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human SFT
Conjugation
Unconjugated
Applications
WB, IHC, FC, IP
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
17 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of SFT in Hela, HL-60 using SFT antibody (1:1000 diluted)
Host or Source
Rabbit

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