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RASGRF1 Recombinant Rabbit mAb

CAT: 0384-BS46974-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS46974-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
GNRP; GRF1; CDC25; GRF55; CDC25L; H-GRF55; PP13187; ras-GRF1
Swiss Prot
Q13972
Reactivity
Human, Rat
Immunogen
A synthetic peptide of human RASGRF1
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:1000-1:5000
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
145 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of CDC25 in Rat Brain lysates using CDC25 antibody (1:1000 diluted) .
Host or Source
Rabbit

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