ITCH Recombinant Rabbit mAb

CAT: 0384-BS46444-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS46444-01Size:50 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
AIF4; AIP4; ADMFD; NAPP1
Swiss Prot
Q96J02
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human ITCH/AIP4
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:1000
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
103 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of ITCH/AIP4 in A549, HL-60 cell lysates using ITCH/AIP4 antibody (1:1000 diluted) .
Host or Source
Rabbit

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