HARS Recombinant Rabbit mAb

• Background :

  Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

• Structure Composition :

  Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Product Name Alternative :

  HRS; CMT2W; USH3B

• Swiss Prot :

  P12081

• Reactivity :

  Human

• Immunogen :

  A synthetic peptide of human HARS

• Conjugation :

  Unconjugated

• Applications :

  WB, IHC, IP

• Purity :

  Affinity Purification

• Modification :

  Unmodification

• Molecular Weight :

  57 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  IgG

• Applications Notes :

  Western blot detection of HARS in K562, Hela cell lysates using HARS antibody (1:1000 diluted) .

• Host or Source :

  Rabbit

• CAS Number :

  9000-83-3