FDPS Recombinant Rabbit mAb

• Background:

  This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008]

• Structure Composition:

  Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Product Name Alternative:

  FPS; FPPS; POROK9

• Swiss Prot:

  P14324

• Reactivity:

  Human

• Immunogen:

  A synthetic peptide of human FDPS

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, FC

• Purity:

  Affinity Purification

• Modification:

  Unmodification

• Molecular Weight:

  48 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot detection of FDPS in CHO-K1 cell lysates using FDPS antibody (1:500 diluted) .

• Host or Source:

  Rabbit

• CAS Number:

  9000-83-3