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Ku70 Recombinant Rabbit mAb

CAT: 0384-BS46186-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS46186-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V (D) J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
ML8; KU70; TLAA; CTC75; CTCBF; G22P1
Swiss Prot
P12956
Reactivity
Human
Immunogen
A synthetic peptide of human Ku70
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, FC, IP
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
70 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of Ku70 in Hela, Ramos using Ku70 antibody (1:1000 diluted)
Host or Source
Rabbit

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