COX2 Recombinant Rabbit mAb

• Background:

  Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]

• Structure Composition:

  Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Product Name Alternative:

  COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS

• Swiss Prot:

  P35354

• Reactivity:

  Human, Rat, Mouse

• Immunogen:

  A synthetic peptide of human COX2

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ICC/IF, IP

• Purity:

  Affinity Purification

• Modification:

  Unmodification

• Molecular Weight:

  74 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of extracts from Mouse spleen tissue at 1:1000.

• Host or Source:

  Rabbit

• CAS Number:

  9000-83-3