NF-KB p65 Recombinant Rabbit mAb

• Background:

  NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

• Structure Composition:

  Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Product Name Alternative:

  P65; NFKB3

• Swiss Prot:

  Q04206, Q04207

• Reactivity:

  Human, Mouse

• Immunogen:

  A synthetic peptide of human NF-kB p65

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ICC/IF, IP

• Purity:

  Affinity Purification

• Modification:

  Unmodification

• Molecular Weight:

  65 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot detection of NF-kB p65 in K562,3T3, Hela cell lysates using NF-kB p65 antibody (1:1000 diluted) .

• Host or Source:

  Rabbit

• CAS Number:

  9000-83-3