SIRT6 Recombinant Rabbit mAb

• Background:

  This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]

• Structure Composition:

  Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Product Name Alternative:

  SIR2L6

• Swiss Prot:

  Q8N6T7

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human SIRT6

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ICC/IF, IP

• Purity:

  Affinity Purification

• Modification:

  Unmodification

• Molecular Weight:

  39 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot detection of SIRT6 in 293T, Jurkat cell lysates using SIRT6 antibody (1:1000 diluted) .

• Host or Source:

  Rabbit

• CAS Number:

  9000-83-3