Transmembrane Protein 173 Recombinant Rabbit mAb

• Background:

  This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

• Structure Composition:

  Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Product Name Alternative:

  ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING

• Swiss Prot:

  Q86WV6

• Reactivity:

  Human

• Immunogen:

  Recombinant protein of human TMEM173

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ICC/IF, FC

• Purity:

  Affinity Purification

• Modification:

  Unmodification

• Molecular Weight:

  40 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot detection of TMEM173 in K562, Rat Brain lysates using TMEM173 antibody (1:1000 diluted) .

• Host or Source:

  Rabbit

• CAS Number:

  9000-83-3