Nibrin Recombinant Rabbit mAb

• Background:

  Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]

• Structure Composition:

  Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Product Name Alternative:

  ATV; NBS; P95; NBS1; AT-V1; AT-V2

• Swiss Prot:

  O60934

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human p95 NBS1

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC

• Purity:

  Affinity Purification

• Modification:

  Unmodification

• Molecular Weight:

  95 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot detection of p95/NBS1 in Hela cell lysates using p95/NBS1 antibody (1:500 diluted) .

• Host or Source:

  Rabbit

• CAS Number:

  9000-83-3