Phospho-LRRK2 (Ser910) Recombinant Rabbit mAb

• Background:

  This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008]

• Structure Composition:

  Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Product Name Alternative:

  PARK8; RIPK7; ROCO2; AURA17; DARDARIN

• Swiss Prot:

  Q5S007

• Reactivity:

  Human

• Immunogen:

  A synthetic phosphopeptide corresponding to residues surrounding Ser910 of human LRRK2

• Conjugation:

  Unconjugated

• Applications:

  WB

• Dilution:

  WB: 1:1000

• Purity:

  Affinity Purification

• Modification:

  Phosphorylated

• Molecular Weight:

  286 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Host or Source:

  Rabbit

• CAS Number:

  9000-83-3