Phospho-EGFR (Tyr1068) Recombinant Rabbit mAb

• Background:

  The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]

• Structure Composition:

  Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Product Name Alternative:

  ERBB; HER1; mENA; ERBB1; PIG61; NISBD2

• Swiss Prot:

  P00533

• Reactivity:

  Human

• Immunogen:

  A synthetic phosphopeptide corresponding to residues surrounding Tyr1068 of human EGFR

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ICC/IF, FC

• Purity:

  Affinity Purification

• Modification:

  Phosphorylated

• Molecular Weight:

  175 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot detection of EGFR (Phospho-Tyr1068) in HepG2 cell lysates using EGFR (Phospho-Tyr1068) antibody (1:1000 diluted) .

• Host or Source:

  Rabbit

• CAS Number:

  9000-83-3