Phospho-FOXO3A (Ser253) Recombinant Rabbit mAb

• Background:

  This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]

• Structure Composition:

  Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Product Name Alternative:

  FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2

• Swiss Prot:

  O43524

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic phosphopeptide corresponding to residues surrounding Ser253 of human FOXO3A

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC

• Purity:

  Affinity Purification

• Modification:

  Phosphorylated

• Molecular Weight:

  82 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot detection of Phospho-FOXO3A (Ser253) in K562, C6 cell lysates using Phospho-FOXO3A (Ser253) antibody (1:1000 diluted) .

• Host or Source:

  Rabbit

• CAS Number:

  9000-83-3