PMS2 mouse monoclonal antibody

• Background:

  This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2008]

• Structure Composition:

  1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  HNPCC4; PMS2CL; PMSL2

• Swiss Prot:

  P54278

• Reactivity:

  Human

• Immunogen:

  Full length human recombinant protein of human PMS2 (NP_000526) produced in HEK293T cell.

• Conjugation:

  Unconjugated

• Applications:

  IF, IHC, WB

• Dilution:

  WB 1:500, IHC 1:150, IF: 1:100

• Purity:

  The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  95.6 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG2b

• Host or Source:

  Mouse

• CAS Number:

  9007-83-4