IFT57 polyclonal antibody

CAT: 0384-BS8765-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS8765-01Size:50 µL
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Background
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8 and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
IFT57; ESRRBL1; HIPPI; MHS4R2
Swiss Prot
Q9NWB7
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human IFT57 (NP_060480.1) .
Conjugation
Unconjugated
Applications
WB
Dilution
WB,1:500 - 1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
49kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Polyclonal Antibodies
Host or Source
Rabbit

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