Products for Research Use Only
RegisterLogin

CRYAA polyclonal antibody

CAT: 0384-BS7816-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS7816-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alpha-A and alpha-B gene products are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Defects in this gene cause autosomal dominant congenital cataract (ADCC) .
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
CRYAA; CRYA1; CTRCT9; HSPB4
Swiss Prot
P02489
Reactivity
Human, Mouse, Rat, Zebrafish
Immunogen
Recombinant fusion protein of human CRYAA (NP_000385.1) .
Conjugation
Unconjugated
Applications
WB, IF/ICC
Dilution
WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
19KDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Polyclonal Antibodies
Host or Source
Rabbit

Related Products

CatalogName
BS41101-01CRYAA Rabbit monoclonal antibody
PPL00651-2aPEGFP-C3-CRYAA
BS75417CRYAB polyclonal antibody
BZ16794-01Polyclonal antibodyPN1 polyclonal antibody
BS75206-01AaaaaASPH polyclonal antibody
BS65563-01Mras polyclonal antibody
BS7930-01TRPM2 polyclonal antibody
BS8744-01TPH2 polyclonal antibody
BS62356-01CSP polyclonal antibody
BS90079ApoER2 polyclonal antibody

Alternative Products

CatalogName
JOT-AP15111-01CRYAA Polyclonal Antibody
GTR18097131CRYAA Rabbit Polyclonal Antibody
A68505-100CRYAA Polyclonal Antibody, FITC Conjugated
A68504-050CRYAA Polyclonal Antibody, HRP Conjugated
WP0618-01U-Blot® CRYAA Polyclonal Antibody
MBS7106879-01CRYAA Antibody

Popular Products