EIF4A1 polyclonal antibody

• Background:

  ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

• Structure Composition:

  1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  EIF4A1; DDX2A; EIF-4A; EIF4A; eIF-4A-I; eIF4A-I

• Swiss Prot:

  P60842

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human eIF4A1 (NP_001407.1) .

• Conjugation:

  Unconjugated

• Applications:

  WB, IF/ICC, IP

• Dilution:

  WB,1:500 - 1:2000|IF/ICC,1:20 - 1:50|IP,1:20 - 1:50

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  48KDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  Polyclonal Antibodies

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4