NBR1 polyclonal antibody

CAT: 0384-BS8985-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS8985-01Size:50 µL
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Background
The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
NBR1;1A1-3B; IAI3B; M17S2; MIG19
Swiss Prot
Q14596
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human NBR1 (NP_005890.2) .
Conjugation
Unconjugated
Applications
WB, IF/ICC, IHC, IP
Dilution
WB,1:500 - 1:2000|IF/ICC,1:50 - 1:100|IHC,1:50 - 1:200| IP, 1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
120KDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Polyclonal Antibodies
Host or Source
Rabbit

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