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Sphingomyelin

CAT: 0804-HY-113498-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-113498-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sphingomyelin is a eukaryotic sphingolipid and one of the major constituents of cell membranes and particularly abundant in the myelin sheath that surrounds neuronal axons. Sphingomyelin plays an important role in cell processes, the regulation of inflammatory responses, and signal transduction. Sphingomyelin metabolism is associated with various central nervous system diseases and Niemann–Pick disease[1][2][3][4].
CAS Number
85187-10-6
UNSPSC
12352211
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Sphingomyelin.html
Purity
99.0
Solubility
Ethanol : 25 mg/mL (ultrasonic)
Smiles
[Sphingomyelin]
References & Citations
[1]Chakraborty M, et al. Sphingomyelin and its role in cellular signaling. Adv Exp Med Biol. 2013;991:1-14.|[2]Schneider N, et al. Sphingomyelin in Brain and Cognitive Development: Preliminary Data. eNeuro. 2019 Aug 6;6 (4) . pii: ENEURO.0421-18.2019.|[3]Bienias K, et al. Regulation of sphingomyelin metabolism. Pharmacol Rep. 2016 Jun;68 (3) :570-81.|[4]Schuchman EH, et al. Types A and B Niemann-Pick disease. Mol Genet Metab. 2017 Jan - Feb;120 (1-2) :27-33.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite; Microbial Metabolite

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