BMP2 polyclonal antibody

• Background :

  This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.

• Structure Composition :

  1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  BDA2; BMP2A; BMP2

• Swiss Prot :

  P12643

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human BMP2 (NP_001191.1) .

• Conjugation :

  Unconjugated

• Applications :

  WB, IHC, IF/ICC

• Dilution :

  WB,1:500 - 1:2000|IHC,1:50 - 1:100|IF/ICC,1:50 - 1:200

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  15KDa/26KDa/45KDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  Polyclonal Antibodies

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4