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FBXL18 polyclonal antibody

CAT: 0384-BS9962M-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS9962M-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
FBL18 (F-box and leucine-rich repeat protein 18), also known as FBXL18, is an 805 amino acid protein that contains an F-box near its N-terminus, followed by several leucine-rich repeats and a transmembrane domain at the C-terminus. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune response, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins and cyclin-dependent kinase inhibitors (CDKNs), for degradation by the proteasome after ubiquitination.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
F-box/LRR-repeat protein 18; F-box and leucine-rich repeat protein 18; FBXL18; FBL18
Swiss Prot
Q96ME1
Reactivity
Human, Mouse
Immunogen
Synthetic peptide corresponding to human FBXL18 aa 750 to C terminus.
Conjugation
Unconjugated
Applications
WB IHC FC
Dilution
WB: 1:500 IHC: 1:50-1:200 FC: 1:50-1:100
Purity
Protein A affinity purified.
Modification
Unmodification
Molecular Weight
~ 40, 88 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
This antibody detects endogenous levels of FBXL18 and does not cross-react with related proteins.
Applications Notes
Western blot analysis of FBXL18 on PC-3M cell lysate using anti-FBXL18 antibody at 1:500 dilution.
Host or Source
Rabbit

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