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RREB1 (E597) polyclonal antibody

CAT: 0384-BS9158-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS9158-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
RREB1 (Ras responsive element binding protein 1), also known as FINB, LZ321 or Zep-1, is a 1,687 amino acid protein that localizes to nuclear speckles and contains fifteen C2H2-type zinc fingers. Expressed in pancreas, heart, liver, placenta, lung, kidney and skeletal muscle, RREB1 functions as a transcription factor that binds to the Ras-responsive element (RRE) of target gene promotors, thereby inducing their transcription. In addition, RREB1 is thought to be involved in Raf/Ras-mediated cell differentiation, possibly by enhancing the expression of Calcitonin, a hormone that is produced by the thyroid gland and plays an essential role in maintaining blood calcium levels. Due to its involvement in cell differentiation events, RREB1 may be involved in Raf/Rasrelated tumor formation. Four isoforms of RREB1 exist due to alternative splicing.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
FINB; Ras-responsive element-binding protein 1; RREB-1; Finger protein in nuclear bodies; Raf-responsive zinc finger protein LZ321; Zinc finger motif enhancer-binding protein 1; Zep-1
Swiss Prot
Q92766
Reactivity
Human, Mouse, Rat
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human RREB1.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:100~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 181 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
RREB1 (E597) polyclonal antibody detects endogenous levels of RREB1 protein.
Applications Notes
Western blot analysis of RREB1 expression in HeLa (A), NIH3T3 (B), rat brain (C) whole cell lysates.
Host or Source
Rabbit

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