DAAM2 polyclonal antibody

• Background:

  DAAM2 (disheveled associated activator of morphogenesis 2), also known as KIAA0381, is a widely expressed 1,068 amino acid protein that contains one DAD domain, one FH1 domain, one FH2 domain and one GBD domain, through which it may play a role in Wnt/Frizzled-associated signaling events. The gene encoding DAAM2 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  Disheveled-associated activator of morphogenesis 2; DAAM2; KIAA0381

• Swiss Prot:

  Q86T65

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant full length Human DAAM2.

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, IF

• Dilution:

  WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 123kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  DAAM2 polyclonal antibody detects endogenous levels of DAAM2 protein.

• Applications Notes:

  Western blot analysis of extracts of various cell lines, using DAAM2 antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4