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GCA polyclonal antibody

CAT: 0384-BS8700-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS8700-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Grancalcin; GCA; GCL
Swiss Prot
P28676
Reactivity
Human, Mouse
Immunogen
Recombinant full length Human GCA.
Conjugation
Unconjugated
Applications
WB IF
Dilution
WB: 1:500~1:2000 IF: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 24kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
GCA polyclonal antibody detects endogenous levels of GCA protein.
Applications Notes
Western blot analysis of extracts of various cell lines, using GCA antibody.
Host or Source
Rabbit

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