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RBBP7 polyclonal antibody

CAT: 0384-BS8620-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS8620-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Histone-binding protein RBBP7; Histone acetyltransferase type B subunit 2; Nucleosome-remodeling factor subunit RBAP46; Retinoblastoma-binding protein 7; RBBP-7; Retinoblastoma-binding protein p46; RBBP7; RBAP46
Swiss Prot
Q16576
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human RBBP7.
Conjugation
Unconjugated
Related Pathways
DNA Methylation
Applications
WB IF IP ChIP
Dilution
WB 1:500 - 1:2000 IF 1:50 - 1:100 IP 1:50 - 1:200 ChIP 1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 48kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
RBBP7 polyclonal antibody detects endogenous levels of RBBP7 protein.
Applications Notes
Western blot analysis of extracts of various cell lines, using RBBP7 antibody.
Host or Source
Rabbit

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