TCAP polyclonal antibody

CAT: 0384-BS8422-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS8422-01Size:50 µL
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Background
Titin, also known as connectin, is a large protein involved in the temporal and spatial control of the assembly of the highly ordered sarcomeres (contractile units) of striated muscle . In addition to sarcomere assembly titin also functions to maintain the structural integrity of the contracting myofibrils within the muscle as well as organizing the machinery for condensation of chromosomes in dividing cells. Titin is a giant protein composed of 27,000 amino acids and contains an autoregulated serine kinase catalytic domain as well as a calcium/calmodulin binding region that are involved in its activation . Activated titin phosphorylates the muscle protein telethonin, a sarcomeric protein abundant in heart and skeletal muscle, implicating titin activity in the reorganization of the cytoskeleton during myofibrillogenesis .
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Telethonin; Titin cap protein; CAP
Swiss Prot
O15273
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human TCAP.
Conjugation
Unconjugated
Applications
WB IF
Dilution
WB: 1:500~1:2000 IF: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 19 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
TCAP polyclonal antibody detects endogenous levels of TCAP protein.
Applications Notes
WesternBlot (WB) analysis of TCAP polyclonal antibody
Host or Source
Rabbit

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