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OGN polyclonal antibody

CAT: 0384-BS8348-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS8348-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The small leucine-rich proteoglycan (SLRP) family of proteins contains various proteins such as Decorin, Biglycan, Fibromodulin, Keratocan, Lumican, Osteoadherin and Osteoglycin. These proteins all have similar functions as they all mediate extracellular matrix organization and act as binding partners of TGFβ. Osteoglycin, which also may be designated osteoinductive factor (OIF), is a secreted protein detected in bone tissues. Osteoglycin induces the formation of bone in conjunction with either TFGβ1 or TGFβ2. The precursor form of the OGN gene product, designated Mimecan, is subject to in situ proteolytic cleavage to yield the mature Osteoglycin.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Mimecan; Osteoglycin; Osteoinductive factor; OIF; OGN; OIF; SLRR3A
Swiss Prot
P20774
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human OGN.
Conjugation
Unconjugated
Applications
WB IHC IF
Dilution
WB 1:500 - 1:2000 IHC 1:100 - 1:200 IF 1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 34 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
OGN polyclonal antibody detects endogenous levels of OGN protein.
Applications Notes
Western blot analysis of extracts of various cell lines, using OGN antibody.
Host or Source
Rabbit

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