SEC24D polyclonal antibody

• Background:

  The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. This gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration. Mutations in this gene have been associated with Cole-Carpenter syndrome, a disorder affecting bone formation, resulting in craniofacial malformations and bones that break easily. Alternative splicing results in multiple transcript variants encoding different isoforms.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  CLCRP2

• Swiss Prot:

  O94855

• Reactivity:

  Human

• Immunogen:

  Recombinant protein of human SEC24D

• Conjugation:

  Unconjugated

• Applications:

  WB, IF

• Dilution:

  WB 1:500 - 1:2000 IF 1:50 - 1:200

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  113kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  SEC24D polyclonal antibody detects endogenous levels of SEC24D protein.

• Applications Notes:

  Western blot analysis of extracts of various cell lines, using SEC24D antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4