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CASP8AP2 polyclonal antibody

CAT: 0384-BS72749-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS72749-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
CED-4; FLASH; RIP25
Swiss Prot
Q9UKL3
Reactivity
Human
Immunogen
Recombinant protein of human CASP8AP2
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:500 - 1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
215kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CASP8AP2 polyclonal antibody detects endogenous levels of CASP8AP2 protein.
Applications Notes
Western blot analysis of extracts of various cell lines, using CASP8AP2 antibody.
Host or Source
Rabbit

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