PLIN3 polyclonal antibody

• Background:

  Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  M6PRBP1; PP17; TIP47

• Swiss Prot:

  O60664

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein of human PLIN3

• Conjugation:

  Unconjugated

• Applications:

  WB IHC

• Dilution:

  WB 1:500 - 1:1000 IHC 1:50 - 1:200

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 47 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  PLIN3 polyclonal antibody detects endogenous levels of PLIN3 protein.

• Applications Notes:

  Western blot analysis of extracts of various cell lines, using PLIN3 antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4